Celiac Disease is a chronic autoimmune enteropathy triggered by gluten ingestion in genetically predisposed individuals. It causes inflammation and destruction of intestinal villi, leading to malabsorption and a variety of gastrointestinal and systemic symptoms. While modern science identifies it as an incurable yet manageable disorder, Ayurveda offers a deeper, more comprehensive healing approach grounded in the concepts of Agni-dushti, Āma, and Grahani Roga.
Celiac Disease: Modern Medical Perspective
Celiac Disease involves an aberrant immune response to gluten—a protein found in wheat, rye, and barley. This immune-mediated reaction damages the lining of the small intestine, particularly the villi, impairing nutrient absorption.
Causes & Pathophysiology
1. Genetic Predisposition
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HLA-DQ2/DQ8 genes are present in over 95% of diagnosed cases.
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A family history of Celiac increases the risk significantly.
2. Immune Mechanism
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Undigested gluten peptides (especially gliadin) cross the gut barrier.
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Deamidated gliadin is presented to T-cells by antigen-presenting cells, leading to inflammatory cytokine release.
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Results in villous atrophy, crypt hyperplasia, and intraepithelial lymphocytosis.
3. Environmental Triggers
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Early gluten exposure
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GI infections
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Gut dysbiosis
Signs & Symptoms
🔹 Gastrointestinal:
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Chronic diarrhea or steatorrhea
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Abdominal bloating, flatulence
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Nausea, vomiting, constipation
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Unexplained weight loss
🔹 Extraintestinal:
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Iron-deficiency anemia
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Osteopenia, osteoporosis
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Dermatitis herpetiformis
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Neurological issues: ataxia, neuropathy
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Infertility, menstrual disturbances
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Delayed puberty or growth in children
Diagnosis
1. Serology:
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Anti-tTG IgA, EMA, DGP antibodies
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Total IgA levels (to rule out IgA deficiency)
2. Endoscopic Biopsy:
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Villous atrophy, crypt elongation
3. Genetic Testing:
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HLA-DQ2/DQ8 genotyping (negative test rules out Celiac Disease)
Modern Management
🔹 Gluten-Free Diet (GFD):
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Avoid wheat, rye, barley
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Consume rice, corn, quinoa, millet
🔹 Supplementation:
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Iron, B12, folate for anemia
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Calcium & Vitamin D for bone health
🔹 Advanced Care:
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Dapsone for dermatitis herpetiformis
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Steroids/immunosuppressants for refractory cases
Ayurvedic Perspective: Celiac Disease as Grahani Roga
Though Celiac Disease is not named in classical Ayurvedic texts, its symptoms and pathophysiology match closely with Grahani Roga (ग्रहणी रोग). The Grahani (small intestine) is the seat of Agni (digestive fire). Dysfunction of Agni leads to Āma formation and weak digestion, resulting in multiple systemic disturbances—paralleling the autoimmune cascade in Celiac Disease.
📚 Classical Reference:
Charaka Chikitsa Sthana 15/57
“अजिर्णाद् ग्रहणीदोषाः, ग्रहणीदोषाद् अजिर्णम्।”
“Indigestion causes dysfunction of Grahani, and a diseased Grahani further perpetuates indigestion.”
This describes a vicious cycle akin to the gluten-triggered autoimmune loop seen in Celiac Disease.
Ayurvedic Nidāna (Causative Factors)
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Ajīrṇa (chronic indigestion)
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Mithyā Ahāra (incompatible or improperly cooked food)
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Adhyashana (eating over undigested food)
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Ati-Rūkṣa, Katu, Tikṣṇa Ahāra (excessively dry, spicy, or pungent food)
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Viruddhāhāra (dietary incompatibilities — gluten may act as such in susceptible persons)
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Stress and Vata aggravation
Grahani Roga Lakṣaṇam (Symptoms)
As per Ashtanga Hridaya Chikitsa 12:
“ग्रहणी रोगस्तु वातपित्तानुबन्धितः, तिक्ताम्लविपाकः, शूल, अरुचि, अतिसार, दुर्बल्यः, अजीर्णलक्षणाः प्राधान्यं भजन्ते।
”
"The disease is associated with Vata-Pitta imbalance, bitter-sour belching, pain, anorexia, diarrhea, fatigue, and indigestion."
Celiac Disease Symptom |
Ayurvedic Parallel |
Chronic diarrhea, steatorrhea |
Atisāra, Picchila Mala |
Abdominal bloating, pain |
Udarashūla, Āmabhāva |
Weight loss, fatigue |
Daurbalya, Alpashakti |
Iron-deficiency anemia |
Pandu Lakṣaṇa |
Delayed growth, malnutrition |
Jatharāgni-māndya, Alpavikāsa |
Skin issues, ulcers |
Raktapradūṣa, Utkleda |
Ayurvedic Chikitsā Sūtra (Line of Treatment)
Treatment is aimed at:
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Agnidīpana (rekindling digestive fire)
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Āma-pācana (digesting toxins)
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Grahī (astringent therapies to restore gut tone)
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Rasāyana (rejuvenation)
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Pañchakarma (biopurification)
🔸 1. Agnidīpana & Āma-pācana
To kindle Agni and eliminate toxins.
Key Herbs/Formulations:
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Trikatu Churna (Pippali, Maricha, Shunthi)
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Chitrakadi Vati, Panchakola Churna
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Hingvashtak Churna
🔸 2. Grahī Chikitsā (Absorbent Therapy)
To manage diarrhea, tone intestines, and enhance nutrient absorption.
Key Remedies:
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Kutajghan Vati, Bilvadi Churna
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Dadimashtaka Churna, Shankha Vati
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Musta, Nagaram, Dhataki, Bilva
🔸 3. Doshashamana (Pacify Vāta & Pitta)
Herbs:
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Chandana, Usheera – Pitta-shamana
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Dashamoola, Bala – Vata-pacification
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Yashtimadhu, Shatavari, Amalaki – Gut healing
🔸 4. Rasāyana Chikitsā
To rejuvenate mucosa, boost immunity, and prevent relapse.
Classical Options:
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Pippalyadi Ghrita, Brahmi Ghrita
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Draksharishta, Ashwagandharishta
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Guduchi Satva, Amalaki Rasayana
📜 Charaka Chikitsa 15/45–47
"Tikta, Deepana, Grahi, Stambhana, Balya, Rasayana dravyas are preferred in Grahani Chikitsa."
🔸 5. Panchakarma Therapies
Only after strength restoration or during remission phase.
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Mridu Virechana (mild purgation): with Haritaki, Trivrit
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Basti Karma (medicated enemas):
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Tikta Ksheera Basti
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Shamana Basti with Dashamoola, Musta
Charaka Siddhi 1/39
“बस्तिः वायुःहरः श्रेष्ठः, पित्तहरं विरेचनम्।
”
"Basti is best for pacifying Vāta, Virechana for Pitta."
Deep Ayurveda’s Holistic Treatment Protocol for Celiac Disease
Deep Ayurveda stands at the forefront of Ayurvedic GI care, offering a powerful synergy of classical principles, GMP-certified herbal formulations, and personalized care for autoimmune gut disorders like Celiac Disease.
✅ Why Deep Ayurveda is the Best Choice in Tricity (Mohali, Panchkula, Chandigarh):
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🌿 Authentic Classical Protocols for Grahani Roga
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🧪 In-house R&D-based proprietary formulations with no preservatives
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🧘♀️ Expert Panchakarma Therapies: Tikta Basti, Rasayana Virechana
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📋 Customized Diet & Lifestyle Plans for gluten-sensitive individuals
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👨⚕️ Experienced Vaidyas offering holistic and root-cause focused consultations
🥗 Ahāra & Vihāra (Diet and Lifestyle for Celiac/Grahani)
✅ Recommended:
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Moong dal khichdi, rice gruel, pomegranate, cow ghee
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Warm, freshly prepared meals in small quantities
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Triphala at bedtime (mild dose)
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Gentle yoga, regular sleep, meditation
❌ To Avoid:
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Gluten grains (wheat, rye, barley)
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Spicy, fermented, fried foods
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Bakery products, cold beverages
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Mental stress, irregular eating habits
🪔 Conclusion
From an Ayurvedic lens, Celiac Disease is not merely a food intolerance but a manifestation of chronic Agni dysfunction, Āma formation, and Tridosha vitiation, predominantly Vata and Pitta. Classical Ayurvedic therapies—Agnidīpana, Āma-pācana, Grahī, Rasāyana, and Panchakarma—offer transformative healing that goes beyond symptom suppression.
Deep Ayurveda, with its integrative approach, authentic formulations, and expert Panchakarma therapies, emerges as the most trusted Ayurvedic center for autoimmune gut disorders in Mohali, Panchkula, and Chandigarh.